Hi I have been on alendronic acid for 7 months I was worried about side effects but have been ok but have noticed a weakness in muscles and am really stiff in mornings and if I sit down even for a short while. Itching in my left shoulder/arm, have gained weight and my mood has changed. Bizarre feelings in my head my heart was pounding and had moments when it seemed out of rhythm. 6.4 Special precautions for storage. Sister told the doc she intends taking Boron. I took my first Alendronic acid tablet last Sunday. Are there any better options to AA which people have found?? It starts after some seemingly minor jaw trauma, but jaw osteonecrosis can quickly decimate a jawbone. Feel quite worried reading all these comments but thoughts Id just let people know that my 90 year old mother has been taking AA plus Adcal for about 8 years after two falls in which her wrists were broken ( falls due to hypotension caused by drug she was currently taking. That was the last tablet I took of that drug. Avoid taking it if you have esophageal or throat conditions. https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA Alendronic acid contains an active ingredient, alendronate sodium, a bisphosphonate. I do have quite a high reading of osteoporosos but I feel I need to know what it really does to the body. Youre description of whip lash injury describes me. I woke up, called my doctor to make sure it was safe to take with a few broken ribs, and I was told yes. Store below 25C. This was after I had in some detail again described to him how prior to a jerking episode, my muscles pulled tighter and tighter before a violent release .. he metaphorically patted me on the head and told me to go and have a massage. I am also diabetic 2 (no drugs diet only) coeliac (wheat and gluten free. The hygienist cleaned my teeth a few weeks ago. I had a scan 6 months ago and have osteoporosis. I compared it with strontium ranelate, which was the drug my sister was taking, and the strontium appeared to have better results. Then seen a doctor over the pains in my head he asked how long Id been taking alendronic when I told him how long Id on them, he was horrified and reported straight away.They discovered I had broken Vertebrae leaning on my spinal cord.Alendronic should be band. Food and beverages (eg, mineral water, coffee, tea, or juice) will decrease the amount of alendronate absorbed by the body. I will not be taking another one! Im 59 and have a very physical job which involves a lot of walking, and I was told by a clinician when I first started treatment that it cant help the spine anyway! Who else out there has a similar story? I stopped taking these tablets after 3 weeks due to pain in my legs and still have it sfter 3 weeks and hoping it will come out of my body soon. No problems with my calcium + vitamin D levels when I started taking medication. Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. I would say) I was suddenly aware of my mouth being transformed into a state where I was unable to move my lips and then my jaw at all. What are we paying the doctors for? However, below are early signs of osteoporosis: Please see your doctor if your family has a history of osteoporosis to assess your risk. Extra C/D also. Your dosing may depend on your age, how severe your bone condition is, other medical conditions you have, and your reaction to the first dose. Menopause in women or low testosterone levels in men, Poor nutrition such as low-intake of calcium and vitamin D, Crohns disease, celiac disease, and other inflammatory bowel conditions that affect your body in absorbing nutrients, Calcium supplements, magnesium, iron, and zinc multivitamins, Cancer medicines such as bevacizumab or thalidomide and if youre undergoing chemotherapy. Conclusions: Alendronic acid once weekly produced greater BMD increases at both hip and spine sites and greater reductions in bone turnover relative to risedronic acid once weekly. My wrists were swollen, aching. It was becoming clear to me at this point that activity brought on my symptoms, and at that time it was extreme activity a session at the gym, a long bike ride, a strenuous walk. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. Glad Im not alone with these problems,thought i was going mad, hi I had zolondronic infusion no problem ,tablets i cant tolerate so I have hit and missed with them ,I told my consultant and the nurses at the hospital but went unanswered said they would sort it ,five weeks a go I fractured my spine so now Im waiting to see what they going to do Ive been honest with them said i skipped a lot cos I felt sick all the time ,Ive opted for infusion,told them that I did tell them ,but now because Ive fractured my spine Im worried that my bone is bad ,bone density scan and hopefully they will sort infusion out for me .I dont like the tablets,I take vitamin d and c .Im trying to help myself just hope its not too late .wouldnt mind I fell off a ladder about two years ago straight onto my back legs and head fell backwards flat and not a broken bone and I had had a density scan just before the fall. Where do you live Jane hope you dont mind me asking. I walked home very gingerly with the dog and later phoned my doctor Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. Stopped alendronic acid for two years during which time I broke my femur in 2014 Hospital June 2014 Spine-2.5 Hip -0.9 Started alendronic acid Jul 2014 for three years Hospital Aug 2017 Spine -2.7 Hip -1.1 Although the scores looked very slightly better at the start they more or less stayed the same for years. My body has been achy since starting them but after taking the A A on Sunday l have been in agony the aches in my joints and my hips have been unbearable and the numbness in my hands and fingers. About 3 hours later, I started to feel weird, sort of dizzy. I had another dexa test in 2018. I have been taking A.A for about 9/10 months. I am aldo taking Calcio with vitamin-D I have had several extrane simpthoms after taking alendronic and had to give it up due to a dental treatment. Results are insufficient to support the use of alendronic acid in paediatric patients with osteogenesis imperfect. When I showed this to my GP, he said that is not correct and the book was wrong. I also broke my hip, which made it even more difficult to do anything at all. My rheumatologist prescribed AS but I dalayed taking as I had lots of dental work to be done. What else can I do to improve my post.menopausal condition? Overdosing may lead to an upset stomach, heartburn, and ulcers. The test showed that I now have osteopenia, but could never get off alendronic as it is due to gluten. Really concerned as Ive never ever had bowel problems!!!! but from the start have not felt well, stabbing pains dental probs,aching joints,My dentist referred me to a specialist to have 3 teeth removed,but i lost it in the chair so scared ! I had another Dxa scan. That is, when the hospital said I had osteoporosis. It usually takes 6-12 months of taking alendronic acid to support your bones. I developed teeth probs just before diagnosis so treatment sounds scary if things are made worse by AA. I was tested for gluten intolerance and was told I was gluten intolerant in 2011. Ostopenia and had a high risk of a fracture. I have an annual blood test at hospital for gluten. From then on the amount of activity needed to bring on the symptoms became less and less, to where I am now. I had to ask the doctor at hospital when I went for gluten test and results. judy. Six hours later, left jaw joint tightness, nerves in teeth/jaw became sensitive (lasted a day), runny stools, dry mouth, calf cramps (at night). Researching I came across Dr Rex Newnham, his story is very interesting, look him up he has written several books re osteoporosis/arthritis, treating them naturally with borax/boron. Dr David Brownstein has written, and talked on YouTube on this subject. I took it on Tuesday. Like a lot of people I was researching AA70 when I came across this group. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! Alendronate is used to prevent and treat osteoporosis. I cant believe the drug companies perscribe this medicine knowing what t doesTo patients,me included I have had the same side effects . Soil degradation is a process in which the value of the land and its biophysical environment is affected by a combination of human actions and non-natural . They are ok and work fine for first few years ! Im 62. My whole body is sore. I quit often find that some of the drugs my doctor has given me gives me bad reactions. Ive been reading all the posts on this forum THINK I might stop altogether does anyone else get these symptoms. This is me! So I duly took the AA70, now on third month. I took them for two Sundays and my legs became painful,Dr said to continue and go back in 2weeks so I took one yesterday and today I feel breathless and giddy. Hi, I am 47 years old and recently found out I have osteopenia every where and osteoprosis in on of my hips. You could suffer from much weaker bones and severe fractures without proper care. This settled after a few days My appointment is on the 23rd August 1017 and I am now very concerned. Should there be a next time I will follow my own advice as I believe we all know our own bodies to a degree of course & I will follow my gut instinct!!! Hi You should be able to have a dexa scan every 5 years. But, remember that without medications, you have to supply your body with enough nutrients and exercise to support and strengthen bone growth. Ive been told to take Allendronicacid. A big thank you to all. Below are the most common things you can do to care for your bones after you stop taking alendronic acid: You probably want to get rid of taking alendronic acid as soon as possible and do the natural way of treatment to avoid serious side effects in the future. But its come to my attention that long term , I was thinking maybe I was dehydrated, so I drank a few bottles of purified water. Im sure they will sound familiar. . I am disappointed in my GP who recommended a NHS Dentist in Melcome Avenue, Wemouth. So I still have not gotten ANY doctor to tell me that the osteo drugs were what CAUSED this but I dont see any other possible cause. No way am I taking another drug, and particularly not this one. Hello Jane, Small movements and small gentle breaths allow me to feel ok and for my muscles to be still. Until recently I only took my Thyroid med. She was a keen walker and is feeling very worried. I was prescribed AA 70mg one per week and took the first dose on Saturday which gave me such severe joint and muscle pain all over my body within 24-36 hours that I was barely able to walk or stand. Hi. Took AA on Sunday and the next night I was in so much pain, I couldnt move. The medicine your doctor has advised you to take, alendronic acid, is one of the bisphosphonates and is given to strengthen fragile bones. I was told i had Oesteoporosis of the spine with high risk of a fracture. I do wish you the very best I only took one pill but think I will stop. From day one I didnt believe that my body needed them but was told that When your taking steroids the additional meds are also needed & I was told this by more than one GP!!! It is strongly linked to a condition called bisphosphonate related osteo necrosis of the jaw if you require any dental treatment while you take it. When I researched Fosamax/drug intolerance I found it is a reported side effect that people (usually women aged 50 70, of course) became intolerant of other drugs whilst having taken Fosamax for 2 5 years. She said for the to call in on monday if there is no improvement. You can, however, lie down after youve eaten your first meal of the day. I expect only the shareholders are enthusiastic about it! This helps to improve bone strength and makes the bone less fragile. She is currently in a lot of pain when she walks. Hi, Ive just been reading through some of the comments as I too have concerns over Alendronic acid tablets. Ive been on Alendronic Acid for about ten years, possibly longer. I am posting this to try and help other , from being in the same situation that I have been in for last 5 months . Im not really happy with the idea of another pill so asked what would happen if I didnt take them and she said I dont know ! Fillings etc are fine but anything more invasive can be really very difficult to manage it. I just took my 8th dose of alendronate sodium 70 mg. The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . Hi Judith But I just couldnt describe it as you have. I am at the moment still recovering from my fracture as it only been 3wks so if anyone reading this have a build up of pressure on your leg whilst taking these awful tablets seek help before the leg breaks as it will the femur is so so painful take care everyone. Alendronic acid monohydrate | C4H15NO8P2 | CID 15585620 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. and he said he would refer for being sedated,as he said he AA are wonderful tablets but do cause jaw and teeth probs along with everything else Am seriously thinking of coming off of them but want to see the outcome of coming off them and how safe it is. A novel process for the preparation of alendronic acid is disclosed. I have been taking alendronic acid and adcal D3 for several months, since starting these drugs I have developed a very dry sore mouth and tongue with much reduced flow of saliva, also I have much reduced sense of taste. I started taking alendronic acid in January 2009. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause. Even before Fosamax was introduced in 1995 as a superior osteoporosis treatment, jaw osteonecrosis has been linked to the bisphosphonate drug family. I just want to feel better. Dont use it. Im wondering how you feel now, a year after stopping the drug, have your symptoms improved? She takes Alendronic Acid every week for a year and a half now for her osteoporosis. This was before I started checking and researching EVERY drug I was told I needed. I had been suffering with a terrible burning tongue for eight months and I also had aching legs, this burning tongue I put down to the gallstones I have got. I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. I shall be bringing these reviews to my GPs attention AND a refusal to even take the first dose! Ive just discovered that lack of it can be at the root of fatigue, depression, low body temperature, and many other issues. My worry at the moment is that I need a new crown in my teeth and do not know if this permitted and if I go ahead will it affect the health of my gums. She sent me to a specialist for a second opinion and he said take it. Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. Anyway, I started to take them three weeks ago and I seem to have been fortunate in that I have had very few side effects but, after reading all these reviews, Im not sure I will carry on as Im fit and healthy with no pain. No tablet is worth taking if no quality of life. You uesly get shake from over active thyroid, I know because that what I have, I have been put on alendronic, I havent taken them yet, its very frigthening, not sure what to do, Im 63 and have gone to the gym most ofy life, I dont want to there guinea pig,. My bloods were fairly normal although my Vit D was just within normal. I will never take drugs like yours again. Mayo Clinic Press. Given ENEMA which got things moving but still having problems so was referred for COLONOSCOPY!! I have done my research an hoping to give up on alendronic and follow the advice in the books. It slows down your body from producing cells that break down your old bones, giving enough time for bone-building cells to spur the growth of new bones. I was wondering if the side effects of the drug actually go away, and if they do, how soon can I expect to see some sort of improvement? Fast forward to 2009. It begins as minor dental problems and can escalate to permanent jaw damage. Unfortunately, Im pretty intolerant to most drugs, other than HRT, which I took for 5 years without any side effects and made me feel fantasticuntil my GP refused to prescribe them once I reached 50. Jan. I thought that I had been duped, once, into taking a drug I probably didnt need for an illness I probably didnt have, a drug that damaged my health. I do wonder if all of this is as a result of being on Seroxat for so long. Bisphosphonates are a class of osteoporosis drugs such as Boniva (ibandronate), Fosamax (alendronate), Actonel (risedronate) and Reclast (zoledronic acid). Already taking Adcal D3 and steroids. Doctor said it was a preemptive measure as my left hip was compromised! It will slow down the breakdown of bones and support the faster growth of new bones in your body. As you age, you will notice changes in your body, such as grayed hair, wrinkles, vision problems, and hearing loss. Bisphosphonates are widely used. A. 25 yrs later Ive had a Dexa scan and was told my spine was crumbling and the reading was far worse than the worst possible. As a follow up to my earlier post, on Feb 21st 2021, I am still experiencing side effects as a result of the ingestion of 1 biphosphonate Alendronic Acid 70g tablet on Sunday Feb 2nd. Alendronic acid, which is a generic drug that is also supplied under the brand name Fosamax Once Weekly (Organon Pharma), is licensed for the treatment of postmenopausal osteoporosis, according to the supply notification. My recent dexa scan showed a deterioration in bone loss in the last three years so much so that I now have osteoporosis in my hip. I wonder if it might be something that could help you Ive attached the link to the video below. Again i had another Dexa scan 2 years ago and it was found i have oesteoporosis in the spine which i feel very worried about it. A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? Alendronic acid may put your pregnancy at risk. I left the surgery with a diagnosis of being on the edge of a clinical depression and a prescription for Seroxat. There is a fine balance struck in order to treat symptoms without curing, so your symptoms are only abated when you take drugs, but if you die, then obviously they make no more money. Whoa, I said, I want to do this with diet and exercise. I am not hoi going to take anymore Alendronic acid tablets. Without the support of new bone tissues, your bones become more porous and fragile, making you prone to bone fractures. they mask the crumbling bones within and only show the outer bone growth, I have decided I really dont want to take these any more but wonder if there are side effects. MY blood pressure became high and I was sent for a ECG on the 29th of November which showed I have at somepoint had a mild heart attack which I was unawear of and have now in December been put on Ramipril 2.7mg and Simvastatin 40mg. I also had pain/soreness behind the eyes and a niggling headache for 48 hours. Fosamax (alendronic acid) is used to treat osteoporosis. Two hours later, I finally could eat, and drink. She told me that all of these drugs, which is just a few, would cause me to have the same side effects. Newsletter archive, Data Based Medicine Global Ltd. Please tell your doctor if youre pregnant or planning to before taking this drug. I suggested, because of the Seroxat link, that I might be sent to a Seroxat specialist. Other symptoms include numbness of the lips which are also dry and sometimes numbness in the chin. I had a complete hysterectomy 24 years ago but could not tolerate HRT therefore was susceptible to osteoporosis but I had slipped through the net according to my doctor and only got a dexa scan in August 2017. She doesnt have osteoporosis but they just put her on these. Im also having episodes of increased heart rate on a regular basis just from walking a short distance. This year the odd finger started my hands have started shaking when I am on my keyboard but for the past 3 months both hands shake. Next morning extreme pain in my back and kidney area. Alendronic acid has been studied in a small number of patients with osteogenesis imperfecta under 18 years of age. As soon as I told the duty doctor it was a possible drug clash, I sensed he immediately lost interest. It belongs to a class of drugs called bisphosphonates. Went to dentist four days ago with toothache my dentist x-rayed my tooth and discovered I have a lot of loss of bone in my jaw cant remember the name for it but it was caused by my treatment for osteoporosis she said she cant take the tooth out as she could cause more damage she said she has to consult with another surgeon first I am in total agony with my tooth and jaw I dont know how much longer I can go on I wont hear anything to Monday so I have all day tomorrow and tomorrow night to suffer I dont know how much longer I can go on help, Ive just started taking Alendronic acid 75mg and for the last 4 days Ive been having really bad indigestion Heartburn and tightness of my chest I have many what I call, low grade headaches with a distinct feeling of fuzziness, disorientation and have problems concentrating. Store the tablet, oral solution, or oral effervescent form of alendronic acid as directed in its packaging. I have been on Sertraline 70mg for a few years and as I have asthma my inhaler has been changed to Beclmetasome 100/6. My partner had videoed two of my jerking episodes for him to see and he asked if he could have copies to show colleagues for their opinions. Your doctor may recommend you go for a regular bone density test using X-rays, dual-energy X-ray absorptiometry (DEXA or DXA), or a special CT scan to diagnose. This was a total surprise to me. Took one tablet within 24hrs experienced labour pains & felt like Id been kicked by a horse in the back continued for 4 days, gradually wore off and I refused to take another Alendronic pill again. I had a fall/fracture side of leg then DEXA scab and told I had osteoporosis, my reading was -2.6 which I believe is just over normal readings. Also take two drugs for cholesterol and statins i rattle !! The next day I felt very ill. Alendronic acid is not for children or teens below 18 years old. Warnings Small blisters on various areas of my body. oscar the grouch eyebrows. Now have constant I was not aware until yesterday that Alendronic could be the cause. Thus, it helps increase bone density, reduce the risk of bone fractures, and treat osteoporosis. I stopped taking alendronic acid straight away and now wake every morning in the hope that there might be some improvement in my condition. . Drinking alcohol for about two standards per day may increase your risk of bone fractures. One thing concerns me! Ive only taken one tablet going to speak to Dr tomorrow. No other cause but the medicine . I was determined that my own actions would build my bones so I only had to take the drug for a short time. I am 55 years old female and took 1 70mg dose of Alendronic Acid 2 weeks ago after being diagnosed with osteoporosis after a Dexa scan. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. We spoke to the GP & asked if she could come off of Alendronic ,so she did, but now she is having problems with her arms, like a muscle ache. Not feel normal anymore, weak dizzy loosing balance and sight too which could also be caused by oprazole to protect stomach. Never in my life have I read as many horror stories and am dumbfounded that medication like this is still being prescribed. I reported the effect the drug had on me to the MHRA. I also went willingly and happily to the gym twice a week and did weekly pilates. But, theres not enough evidence on this claim. I thought I was intelligent and assertive enough that it couldnt possibly happen to me a second time. Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! Clinical trial results suggest an increased risk of atrial fibrillation for zoledronic acid (Aclasta ), pamidronic acid, and possibly for alendronic acid, although the balance-risk remains. This caused the bone to shatter like glass ! While there is no cure for osteoporosis, your doctor will give you a treatment plan like taking medications and lifestyle changes. It treats osteoporosis in postmenopausal women and men at high risk of fractures. If you are taking this tablet once a week . My idea of a short walk had always been an hour and a half in the woods with my dog my favourite footwear was my walking boots. Ive only had one tablet of the Alendronic Acid yesterday, but seem to have quite a few of the side effects so wont have another again, and am miffed to see that people have problems for weeks even after one tablet. It hurts to walk on my feet. Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. But, because you naturally produce vitamin D3, your doctor might not recommend you take supplements unless you have a deficiency. Editorial Note: We want any accounts of adverse or interesting events on drugs or new uses for drugs from people on them or doctors, pharmacists or others trying to manage the effects of drugs. The strange thing is that as soon as I read: That is exactly the reaction I had years ago to Metoclopramide the anti sickness drug. Please check with your doctor before stopping taking alendronic acid and switching to alternative treatments. I urge you to Look into his work for yourselves. Alendronic Acid Has Destroyed My Life. September 2020 Diagnosed with PMR & prescribed Prednisolone + ADCAL3D +Alendronic Acid. But first, you should learn more about osteoporosis. If I took slow shallow breaths the pain was bearable. Energice is a vitamin infused Premium Isotonic ice bar scientifically formulated with Electrolytes, B Vitamins (B3, B5, B6, B12) and Potassium. Below is everything you need to know about alendronic acid, commonly prescribed by doctors to treat bone conditions. I also have arthritis in my thumbs. What an awful time you are having my sympathy goes out to you. But no issue with my teeth. where do I go from here, the last thing I want is dentures !! Back to see the same neurologist whose diagnosis this time was that my muscles were very tight so I must be stressed, and if I wasnt already taking it, he would prescribe Seroxat! Due to cutbacks now prescribed unnamed Alendronic and feel absolutely ghastly. The current protocol for this drug is for 3-5 years maximum. Peripheral neuropathy in the hands and fingers. HI all I fractured my wrist in October had a dxa scan and was told I had osteoporosis. Thank all of you for your posts. Land degradation also has serious knock-on effects for humans, such as malnutrition, disease, forced migration, cultural damage, and even war. Started on Fosamax l6 years ago. Can you keep us posted on whether it goes down again, and if it does whether you or anyone can work out what it is about the drug is causing this to happen and what your doctor suggests when you get to talk to him. Shingles 6 months ago and Dr. says this is result of shingles. If you suddenly stop taking the drug, you might experience severe side effects, putting you at high risk of more bone fractures. Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Have other peoples side effects, particularly bone and muscle pain gone away after discontinuing this drug. In addition, previous side effects were swellings and wealds all over, itching and bloatedness. Dosage instructions, including remaining upright for at least 30 minutes and taking with a full glass of water, must be strictly followed. I dont know if this is due to alendronic acid or the letrozole I am taking for breast cancer.